Down's syndrome is strongly associated with coeliac disease Dissertation

Down's syndrome is strongly associated with coeliac disease - Dissertation Example The remaining fifty five respondents were each matched with control patients based on sex, age and residence. In addition, in the research, both positive IgG and IgA, anti-gliadin levels were got by endoscopial duodenal biopsy of the given patients and initial titres taken. Initially, only twenty one patients plus two from the control group showed raised levels of IgG and IgA antibodies. When tissue samples were obtained from 18 of the patients, it was found out that only two shoed characteristic lymphocytic infiltration that did not qualify for the diagnosis of coeliac disease. In addition, they also found two giardiasis, while eight of the rest were normal. Furthermore, in one of the obtained tissue, analysis was not done since it had not be obtained well. In the analysis, few differences were found to occur between the various subgroups in their hematological, anthropomorphic and biochemical findings. It was found out that the prevalence of coeliac disease in Down’s syndrom e patients was higher than in the controlled group. In the controlled group, coeliac disease occurrence was very little as compared to the population that had down’s syndrome. In another research conducted by Lenshin et. al. in 2004, while studying coeliac disease, discovered that Down’s syndrome patients were more likely to suffer from the condition and attributed it to their autoimmune state. Lorete et.al , on the other hand, was studying the relationship of celiac disease in adolescents and children and found a link too to those having Down’s syndrome.